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Did you mean milk and ncapg (7 results)?
CCNB2, CDC20, AURKA, TOP2A, MELK, NCAPG, KIF20A, UBE2C, PRC1, and ASPM May Be Potential Therapeutic Targets for Hepatocellular Carcinoma Using Integrated Bioinformatic Analysis.
Yang Z, Wu X, Li J, Zheng Q, Niu J, Li S. Yang Z, et al. Int J Gen Med. 2021 Dec 22;14:10185-10194. doi: 10.2147/IJGM.S341379. eCollection 2021. Int J Gen Med. 2021. PMID: 34992437 Free PMC article.
CONCLUSION: Our study suggests that CCNB2, CDC20, AURKA, TOP2A, MELK, NCAPG, KIF20A, UBE2C, PRC1, and ASPM were overexpressed in HCC compared with normal liver tissue. ...
CONCLUSION: Our study suggests that CCNB2, CDC20, AURKA, TOP2A, MELK, NCAPG, KIF20A, UBE2C, PRC1, and ASPM were overexpressed …
Identification of Core Gene Expression Signature and Key Pathways in Colorectal Cancer.
Ding X, Duan H, Luo H. Ding X, et al. Front Genet. 2020 Feb 21;11:45. doi: 10.3389/fgene.2020.00045. eCollection 2020. Front Genet. 2020. PMID: 32153633 Free PMC article.
RESULTS: We identified 683 shared DEGs (420 upregulated and 263 downregulated), and the top twenty genes (CDK1, CCNA2, TOP2A, PLK1, MAD2L1, AURKA, BUB1B, UBE2C, TPX2, RRM2, KIF11, NCAPG, MELK, NUSAP1, MCM4, RFC4, PTTG1, CHEK1, CEP55, DTL) were selected by integrated …
RESULTS: We identified 683 shared DEGs (420 upregulated and 263 downregulated), and the top twenty genes (CDK1, CCNA2, TOP2A, PLK1, MAD2L1, …
Identification of druggable hub genes and key pathways associated with cervical cancer by protein-protein interaction analysis: An in silico study.
Asadzadeh A, Ghorbani N, Dastan K. Asadzadeh A, et al. Int J Reprod Biomed. 2023 Nov 24;21(10):809-818. doi: 10.18502/ijrm.v21i10.14536. eCollection 2023 Oct. Int J Reprod Biomed. 2023. PMID: 38077941 Free PMC article.
RESULTS: Based on the degree method, 10 key genes were known as the hub genes after the screening of PPI networks by the CytoHubba plugin. NCAPG, KIF11, TTK, PBK, MELK, ASPM, TPX2, BUB1, TOP2A, and KIF2C are the key genes, of which 5 genes (KIF11, TTK, PBK, MELK …
RESULTS: Based on the degree method, 10 key genes were known as the hub genes after the screening of PPI networks by the CytoHubba plugin. …
Identifying potential prognosis markers in hepatocellular carcinoma via integrated bioinformatics analysis and biological experiments.
Hu X, Zhou J, Zhang Y, Zeng Y, Jie G, Wang S, Yang A, Zhang M. Hu X, et al. Front Genet. 2022 Jul 19;13:942454. doi: 10.3389/fgene.2022.942454. eCollection 2022. Front Genet. 2022. PMID: 35928445 Free PMC article.
Results: Through integrated bioinformatics analysis, we found that the upregulated DEGs were related to cell cycle and cell division, while the downregulated DEGs were associated with various metabolic processes and complement cascade. RRM2, MAD2L1, MELK, NCAPG, and …
Results: Through integrated bioinformatics analysis, we found that the upregulated DEGs were related to cell cycle and cell division, while …
Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis.
Zhou L, Du Y, Kong L, Zhang X, Chen Q. Zhou L, et al. Onco Targets Ther. 2018 Apr 4;11:1861-1869. doi: 10.2147/OTT.S156737. eCollection 2018. Onco Targets Ther. 2018. PMID: 29670361 Free PMC article.
A significant module including nine hub genes, ASPM, AURKA, CCNB2, CDKN3, MELK, NCAPG, NUSAP1, PRC1, and TOP2A, was detected from the PPI network by Molecular Complex Detection. ...The relative expression levels of nine genes (ASPM, AURKA, CDKN3, MELK, NCA …
A significant module including nine hub genes, ASPM, AURKA, CCNB2, CDKN3, MELK, NCAPG, NUSAP1, PRC1, and TOP2A, was detected f …
Identifying key genes and screening therapeutic agents associated with diabetes mellitus and HCV-related hepatocellular carcinoma by bioinformatics analysis.
Sufyan M, Ali Ashfaq U, Ahmad S, Noor F, Hamzah Saleem M, Farhan Aslam M, El-Serehy HA, Aslam S. Sufyan M, et al. Saudi J Biol Sci. 2021 Oct;28(10):5518-5525. doi: 10.1016/j.sjbs.2021.07.068. Epub 2021 Jul 30. Saudi J Biol Sci. 2021. PMID: 34588861 Free PMC article.
PPI network obtained from STRING were subjected to Cytoscape plugin cytoHubba, and top 10 genes (AURKA, JUN, AR, MELK, NCOA2, CENPF, NCAPG, PCK1, RAD51AP1, and GTSE1) were chosen as the target hub genes based on the highest degree of connectivity. Furthermore, 47 dr …
PPI network obtained from STRING were subjected to Cytoscape plugin cytoHubba, and top 10 genes (AURKA, JUN, AR, MELK, NCOA2, CENPF, …
Screening and authentication of molecular markers in malignant glioblastoma based on gene expression profiles.
Zou YF, Meng LB, He ZK, Hu CH, Shan MJ, Wang DY, Yu X. Zou YF, et al. Oncol Lett. 2019 Nov;18(5):4593-4604. doi: 10.3892/ol.2019.10804. Epub 2019 Sep 4. Oncol Lett. 2019. PMID: 31611967 Free PMC article.
Its significant module had 10 hub genes, and CDK1, BUB1B, NDC80, NCAPG, BUB1, CCNB1, TOP2A, DLGAP5, ASPM and MELK were significantly associated with carcinogenesis and the development of GBM. ...
Its significant module had 10 hub genes, and CDK1, BUB1B, NDC80, NCAPG, BUB1, CCNB1, TOP2A, DLGAP5, ASPM and MELK were signifi …
Comprehensive Bioinformatics Analysis of mRNA Expression Profiles and Identification of a miRNA-mRNA Network Associated with the Pathogenesis of Low-Grade Gliomas.
Wang M, Cui Y, Cai Y, Jiang Y, Peng Y. Wang M, et al. Cancer Manag Res. 2021 Jun 29;13:5135-5147. doi: 10.2147/CMAR.S314011. eCollection 2021. Cancer Manag Res. 2021. PMID: 34234557 Free PMC article.
Finally, the potential miRNA-mRNA networks were further validated in CGGA (Chinese Glioma Genome Atlas) datasets and clinical specimens by qRT-PCR. RESULTS: In our results, six hub genes, MELK, NCAPG, KIF4A, NUSAP1, CEP55, and TOP2A, were ultimately identified. Two …
Finally, the potential miRNA-mRNA networks were further validated in CGGA (Chinese Glioma Genome Atlas) datasets and clinical specimens by q …
Identification of Drug Targets and Agents Associated with Hepatocellular Carcinoma through Integrated Bioinformatics Analysis.
Hossen MA, Reza MS, Harun-Or-Roshid M, Islam MA, Siddika MA, Mollah MNH. Hossen MA, et al. Curr Cancer Drug Targets. 2023;23(7):547-563. doi: 10.2174/1568009623666230214100159. Curr Cancer Drug Targets. 2023. PMID: 36786134
RESULTS: We identified 160 common DEGs (cDEGs) from three independent mRNA expression datasets in which ten cDEGs (CDKN3, TK1, NCAPG, CDCA5, RACGAP1, AURKA, PRC1, UBE2T, MELK, and ASPM) were selected as Hub-cDEGs. ...
RESULTS: We identified 160 common DEGs (cDEGs) from three independent mRNA expression datasets in which ten cDEGs (CDKN3, TK1, NCAPG, …
Bioinformatics analysis to determine the prognostic value and prospective pathway signaling of miR-126 in non-small cell lung cancer.
Jiao Z, Yu A, He X, Xuan Y, Zhang H, Wang G, Shi M, Wang T. Jiao Z, et al. Ann Transl Med. 2020 Dec;8(24):1639. doi: 10.21037/atm-20-7520. Ann Transl Med. 2020. PMID: 33490151 Free PMC article.
In the PPI network analysis, 3 of 10 identified hub genes, namely NCAPG, MELK, and KIAA0101, were obviously related to poor prognosis in NSCLC; the survival rate was low among patients with high expression levels of these genes. ...
In the PPI network analysis, 3 of 10 identified hub genes, namely NCAPG, MELK, and KIAA0101, were obviously related to poor pr …
14 results